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human DPF2 shRNA silencing AAV

Name 
AAV-h-DPF2-shRNA
Cat No 
shAAV-207271
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DPF2.

shAAV-207271
AAV-h-DPF2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DPF2 (double PHD fingers 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
apoptosis response zinc finger protein; BAF45D; BRG1-associated factor 45D; CSS7; D4, zinc and double PHD fingers family 2; protein requiem; REQ; requiem, apoptosis response zinc finger; UBID4; ubi-d4; zinc finger protein ubi-d4
Description (eCommerce)
DPF2 (zinc and double PHD fingers family 2) is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors [taken from NCBI Entrez Gene (Gene ID: 5977)].
Description (Vector)
DPF2 is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
Gene ID
5977
Gene Name (eCommerce)
double PHD fingers 2
Gene Name (Vector)
double PHD fingers 2
Gene Symbol
DPF2
HGNC ID
HGNC:9964
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1176
ORF Size (bp)
1176 bp
Protein Name (eCommerce)
Zinc finger protein ubi-d4
RefSeq ID
NM_006268
RefSeq Synonyms
NM_006268, NM_001330308, BC014889,
Research Areas
Apoptosis,Immunology,Signal Transduction,TNF Signaling,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
DPF2 (zinc and double PHD fingers family 2) is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors [taken from NCBI Entrez Gene (Gene ID: 5977)].
UniGene ID
Hs.13495
UniProt ID (eCommerce)
Q92785

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.