human DOCK8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DOCK8.
shAAV-207235
AAV-h-DOCK8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DOCK8 (dedicator of cytokinesis 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HEL-205; MRD2; ZIR8
Description (Vector)
DOCK8 encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
81704
Gene Name (Vector)
dedicator of cytokinesis 8
Gene Symbol
DOCK8
HGNC ID
HGNC:19191
ORF Size (aa)
6000
ORF Size (bp)
6000 bp
RefSeq ID
NM_203447
RefSeq Synonyms
NM_203447, NM_001193536, NM_001190458, BC143929, BC130518,
Species
human
UniGene ID
Hs.132599
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.