human DNASE1L1 shRNA silencing AAV

Name
AAV-h-DNASE1L1-shRNA

Cat No
shAAV-207187

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human DNASE1L1.

shAAV-207187

AAV-h-DNASE1L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNASE1L1 (deoxyribonuclease 1 like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DNAS1L1; DNASEX; DNL1L; G4.8; XIB

Description (Vector)

DNASE1L1 encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

Gene ID

1774

Gene Name (Vector)

deoxyribonuclease 1 like 1

Gene Symbol

DNASE1L1

HGNC ID

HGNC:2957

ORF Size (aa)

909

ORF Size (bp)

909 bp

RefSeq ID

NM_006730

RefSeq Synonyms

NM_006730, NM_001303620, NM_001009934, NM_001009933, NM_001009932, BC028092, BC001561,

Species

human

UniGene ID

Hs.401929

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.