human DNAJC24 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DNAJC24.
shAAV-207164
AAV-h-DNAJC24-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DNAJC24 (DnaJ heat shock protein family (Hsp40) member C24). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DPH4; JJJ3; ZCSL3
Description (Vector)
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 (PubMed 15485916)).(supplied by OMIM, Mar 2008)
Gene ID
120526
Gene Name (Vector)
DnaJ heat shock protein family (Hsp40) member C24
Gene Symbol
DNAJC24
HGNC ID
HGNC:26979
ORF Size (aa)
447
RefSeq ID
NM_181706
RefSeq Synonyms
NM_181706, BC063804, BC036571,
Species
human
UniGene ID
Hs.718544
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.