human DNAJA2 shRNA silencing AAV

Name
AAV-h-DNAJA2-shRNA

Cat No
shAAV-207118

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DNAJA2.

shAAV-207118

AAV-h-DNAJA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNAJA2 (DnaJ heat shock protein family (Hsp40) member A2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CPR3; DJ3; DJA2; DNAJ; DNJ3; HIRIP4; PRO3015; RDJ2

Description (Vector)

DNAJA2 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.

Gene ID

10294

Gene Name (Vector)

DnaJ heat shock protein family (Hsp40) member A2

Gene Symbol

DNAJA2

HGNC ID

HGNC:14884

ORF Size (aa)

1239

ORF Size (bp)

1239 bp

RefSeq ID

NM_005880

RefSeq Synonyms

NM_005880, BC015809, BC013044,

Species

human

UniGene ID

Hs.368078

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.