human DNAI2 shRNA silencing AAV

Name
AAV-h-DNAI2-shRNA

Cat No
shAAV-207116

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human DNAI2.

shAAV-207116

AAV-h-DNAI2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNAI2 (dynein axonemal intermediate chain 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CILD9; DIC2

Description (Vector)

DNAI2 belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene ID

64446

Gene Name (Vector)

dynein axonemal intermediate chain 2

Gene Symbol

DNAI2

HGNC ID

HGNC:18744

ORF Size (aa)

1209

ORF Size (bp)

1209 bp

RefSeq ID

NM_023036

RefSeq Synonyms

NM_023036, NM_001172810, BC039582, BC033013,

Species

human

UniGene ID

Hs.147472

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.