human DMRT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DMRT1.
shAAV-207095
AAV-h-DMRT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DMRT1 (doublesex and mab-3 related transcription factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CT154; DMT1
Description (Vector)
DMRT1 is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. DMRT1 exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
Gene ID
1761
Gene Name (Vector)
doublesex and mab-3 related transcription factor 1
Gene Symbol
DMRT1
HGNC ID
HGNC:2934
ORF Size (aa)
1122
ORF Size (bp)
1122 bp
RefSeq ID
NM_021951
RefSeq Synonyms
NM_021951, BC040847,
Species
human
UniGene ID
Hs.98586
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.