human DIABLO shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DIABLO.
shAAV-206981
AAV-h-DIABLO-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DIABLO (diablo IAP-binding mitochondrial protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DFNA64; SMAC
Description (Vector)
DIABLO encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein.
Gene ID
56616
Gene Name (Vector)
diablo IAP-binding mitochondrial protein
Gene Symbol
DIABLO
HGNC ID
HGNC:21528
ORF Size (aa)
720
ORF Size (bp)
720 bp
RefSeq ID
NM_019887
RefSeq Synonyms
NM_138930, NM_138929, NM_019887, NM_001278342, NM_001278304, NM_001278303, NM_001278302, BC095468, BC011909,
Species
human
UniGene ID
Hs.169611
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.