human DHODH shRNA silencing AAV

Name 
AAV-h-DHODH-shRNA
Cat No 
shAAV-206939
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DHODH.

shAAV-206939
AAV-h-DHODH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DHODH (dihydroorotate dehydrogenase (quinone)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DHOdehase; POADS; URA1
Description (Vector)
DHODH catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.
Gene ID
1723
Gene Name (Vector)
dihydroorotate dehydrogenase (quinone)
Gene Symbol
DHODH
HGNC ID
HGNC:2867
ORF Size (aa)
1188
ORF Size (bp)
1188 bp
RefSeq ID
NM_001361
RefSeq Synonyms
NM_001361, BC065245,
Species
human
UniGene ID
Hs.654427

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.