human DGKQ shRNA silencing AAV

Name
AAV-h-DGKQ-shRNA

Cat No
shAAV-206927

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DGKQ.

shAAV-206927

AAV-h-DGKQ-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DGKQ (diacylglycerol kinase theta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DAGK; DAGK4; DAGK7

Description (Vector)

DGKQ contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction.

Gene ID

1609

Gene Name (Vector)

diacylglycerol kinase theta

Gene Symbol

DGKQ

HGNC ID

HGNC:2856

ORF Size (aa)

2829

ORF Size (bp)

2829 bp

RefSeq ID

NM_001347

RefSeq Synonyms

NM_001347, BC063801,

Species

human

UniGene ID

Hs.584858

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.