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human DENND4A shRNA silencing AAV

Name 
AAV-h-DENND4A-shRNA
Cat No 
shAAV-206873
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DENND4A.

shAAV-206873
AAV-h-DENND4A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DENND4A (DENN domain containing 4A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
c-myc promoter binding protein; C-myc promoter-binding protein; DENN domain-containing protein 4A; DENN/MADD domain containing 4A; IRLB; MYCPBP
Description (eCommerce)
DENN/MADD domain containing 4A (DENND4A) is also known as c-myc promoter-binding protein and IRLB. The DENND4A product binds to the ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
Gene ID
10260
Gene Name (eCommerce)
DENN domain containing 4A
Gene Name (Vector)
DENN domain containing 4A
Gene Symbol
DENND4A
HGNC ID
HGNC:24321
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5592
ORF Size (bp)
5592 bp
Protein Name (eCommerce)
C-myc promoter-binding protein
RefSeq ID
NM_005848
RefSeq Synonyms
NM_005848, NM_001320835, NM_001144823, BC041706,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
DENN/MADD domain containing 4A (DENND4A) is also known as c-myc promoter-binding protein and IRLB. The DENND4A product binds to the ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
UniGene ID
Hs.654567
UniProt ID (eCommerce)
Q7Z401

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.