human DEF6 shRNA silencing AAV

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Recombinant AAV

AAV-ITR

AAV2

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Gene Details

Species

Human

Gene Symbol

DEF6

Gene Name

DEF6, guanine nucleotide exchange factor

Gene ID

50619

Gene Synonyms

IBP; SLAT; SWAP70L

ORF Size

1896 bp

RefSeq#

NM_022047

Gene Description

DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 (PubMed 12923183)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.15476

HGNC ID

HGNC:2760