human DEDD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DEDD.
shAAV-206785
AAV-h-DEDD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DEDD (death effector domain containing). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CASP8IP1; DEDD1; DEFT; FLDED1; KE05
Description (Vector)
DEDD encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
Gene ID
9191
Gene Name (Vector)
death effector domain containing
Gene Symbol
DEDD
HGNC ID
HGNC:2755
ORF Size (aa)
957
ORF Size (bp)
957 bp
RefSeq ID
NM_032998
RefSeq Synonyms
NM_032998, NM_001330765, NM_001039712, NM_001039711, BC016724, BC013910,
Species
human
UniGene ID
Hs.146406
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.