human DDX52 shRNA silencing AAV

Name
AAV-h-DDX52-shRNA

Cat No
shAAV-206768

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DDX52.

shAAV-206768

AAV-h-DDX52-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DDX52 (DExD-box helicase 52). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ATP-dependent RNA helicase ROK1-like; DEAD (Asp-Glu-Ala-Asp) box polypeptide 52; DEAD box protein 52; DEAD-box helicase 52; HUSSY19; probable ATP-dependent RNA helicase DDX52; ROK1

Description (eCommerce)

DDX52 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes.

Gene ID

11056

Gene Name (eCommerce)

DExD-box helicase 52

Gene Name (Vector)

DExD-box helicase 52

Gene Symbol

DDX52

HGNC ID

HGNC:20038

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1800

ORF Size (bp)

1800 bp

Protein Name (eCommerce)

Probable ATP-dependent RNA helicase DDX52

RefSeq ID

NM_007010

RefSeq Synonyms

NM_007010, NM_001291476, BC041785,

Research Areas

Helicase Activity,RNA Binding,RNA Processing

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

DDX52 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes.

UniGene ID

Hs.590937

UniProt ID (eCommerce)

Q9Y2R4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.