human CYCS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CYCS.
shAAV-206413
AAV-h-CYCS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CYCS (cytochrome c, somatic). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CYC; cytochrome c; HCS; THC4
Description (eCommerce)
Cytochrome C (CYCS) is a small heme protein that functions as a central component of the electron transport chain in mitochondria. Cytochrome C (CYCS) associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis [taken from NCBI Entrez Gene (Gene ID: 54205)].
Description (Vector)
CYCS encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.
Gene ID
54205
Gene Name (eCommerce)
cytochrome c, somatic
Gene Name (Vector)
cytochrome c, somatic
Gene Symbol
CYCS
HGNC ID
HGNC:19986
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
318
Protein Name (eCommerce)
Cytochrome c
RefSeq ID
NM_018947
RefSeq Synonyms
NM_018947, BC071761, BC070346, BC070156, BC068464, BC067222, BC022330, BC021994, BC016006, BC015130, BC014361, BC014359, BC009607, BC009602, BC009587, BC009582, BC009579, BC009578, BC008477, BC008475, BC005299,
Research Areas
Alzheimer's Disease,Amyotrophic Lateral Sclerosis (ALS),Apoptosis,B-cell Receptor Signaling,Cancer,Cardiology,Cardiovascular,CD95/FAS Signaling,Cell Cycle,Colorectal Cancer,DNA Damage/Repair,Host-Virus Interactions,Huntington's Disease,Immunology,Lung Cancer,Metabolism/Metabolic Process,Mitochondrion,mTOR Signaling,Neurobiology,Neurodegeneration,p53 Signaling,Parkinson's Disease,Signal Transduction,TNF Signaling
Research Areas (Faceted)
cancer,signal_transduction,neurobiology,cell_biology,signal_transduction,immunology,cardiovascular,signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease,neurobiology,immunology,metabolism,cell_biology,signal_transduction,metabolism,neurobiology,signal_transduction,neurobiology
Species
human
Target Sentence
Cytochrome C (CYCS) is a small heme protein that functions as a central component of the electron transport chain in mitochondria. Cytochrome C (CYCS) associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis [taken from NCBI Entrez Gene (Gene ID: 54205)].
UniGene ID
Hs.617193
UniProt ID (eCommerce)
P99999
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.