human CXCR4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CXCR4.
shAAV-206344
AAV-h-CXCR4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CXCR4 (chemokine (C-X-C motif) receptor 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD184; D2S201E; FB22; HM89; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM;
Description (Vector)
CXCR4 encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
7852
Gene Name (Vector)
chemokine (C-X-C motif) receptor 4
Gene Symbol
CXCR4
HGNC ID
HGNC:2561
ORF Size (aa)
1059
ORF Size (bp)
1059 bp
RefSeq ID
NM_003467
RefSeq Synonyms
NM_003467, NM_001008540, BC020968,
Species
human
UniGene ID
Hs.593413
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.