human CXCL1 shRNA silencing AAV

Name 
AAV-h-CXCL1-shRNA
Cat No 
shAAV-206326
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CXCL1.

shAAV-206326
AAV-h-CXCL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CXCL1 (C-X-C motif chemokine ligand 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1
Description (Vector)
CXCL1 encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
Gene ID
2919
Gene Name (Vector)
C-X-C motif chemokine ligand 1
Gene Symbol
CXCL1
HGNC ID
HGNC:4602
ORF Size (aa)
324
RefSeq ID
NM_001511
RefSeq Synonyms
NM_001511, BC011976,
Species
human
UniGene ID
Hs.789

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.