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human CTSS shRNA silencing AAV

Name 
AAV-h-CTSS-shRNA
Cat No 
shAAV-206280
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CTSS.

shAAV-206280
AAV-h-CTSS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CTSS (cathepsin S). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
CTSS, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
1520
Gene Name (Vector)
cathepsin S
Gene Symbol
CTSS
HGNC ID
HGNC:2545
ORF Size (aa)
996
ORF Size (bp)
996 bp
RefSeq ID
NM_004079
RefSeq Synonyms
NM_004079, NM_001199739, BC002642,
Species
human
UniGene ID
Hs.181301

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.