human CSTF1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CSTF1.
shAAV-206191
AAV-h-CSTF1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CSTF1 (cleavage stimulation factor subunit 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CF-1 50 kDa subunit; cleavage stimulation factor 50 kDa subunit; cleavage stimulation factor subunit 1; cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kD; cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa; CSTF 50 kDa subunit; CstF-50; CstFp50
Description (eCommerce)
CSTF50 is one of three subunits that comprise the cleavage stimulation factor (CSTF) complex. CSTF is part of the polyadenylation machinery that adds adenylate residues to the 3’-ends of eukaryotic pre-mRNAs. In the CSTF complex, CSTF50 interacts with CSTF77 (CSTF3), and CSTF64 (CSTF2).
Description (Vector)
CSTF1 encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
Gene ID
1477
Gene Name (eCommerce)
cleavage stimulation factor subunit 1
Gene Name (Vector)
cleavage stimulation factor subunit 1
Gene Symbol
CSTF1
HGNC ID
HGNC:2483
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1296
ORF Size (bp)
1296 bp
Protein Name (eCommerce)
Cleavage stimulation factor subunit 1
RefSeq ID
NM_001324
RefSeq Synonyms
NM_001324, NM_001033522, NM_001033521, BC007425, BC001011,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Signal Transduction,Spliceosome
Research Areas (Faceted)
signal_transduction,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
CSTF50 is one of three subunits that comprise the cleavage stimulation factor (CSTF) complex. CSTF is part of the polyadenylation machinery that adds adenylate residues to the 3’-ends of eukaryotic pre-mRNAs. In the CSTF complex, CSTF50 interacts with CSTF77 (CSTF3), and CSTF64 (CSTF2).
UniGene ID
Hs.172865
UniProt ID (eCommerce)
Q05048
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.