human CST2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CST2.
shAAV-206172
AAV-h-CST2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CST2 (cystatin SA). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma.
Gene ID
1470
Gene Name (Vector)
cystatin SA
Gene Symbol
CST2
HGNC ID
HGNC:2474
ORF Size (aa)
426
RefSeq ID
NM_001322
RefSeq Synonyms
NM_001322, BC062679,
Species
human
UniGene ID
Hs.669305
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.