human CSNK1D shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CSNK1D.
shAAV-206140
AAV-h-CSNK1D-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CSNK1D (casein kinase 1 delta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ASPS; casein kinase I; casein kinase I isoform delta; CKId; CKIdelta; CKI-delta; FASPS2; HCKID; tau-protein kinase CSNK1D
Description (eCommerce)
CKI delta is a member of the casein kinase 1 (CK1) serine/threonine kinase family of proteins. In mammals, there are seven distinct genes that represent the CK1 family: alpha, beta, gamma-1, gamma-2, gamma-3, delta, and epsilon. CKI delta phosphorylates a number of proteins some of which include the circadian proteins period 1 and period 2. CKI delta is also involved in the Wnt signaling pathway.
Description (Vector)
CSNK1D is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
1453
Gene Name (eCommerce)
casein kinase 1 delta
Gene Name (Vector)
casein kinase 1 delta
Gene Symbol
CSNK1D
HGNC ID
HGNC:2452
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1230
ORF Size (bp)
1230 bp
Protein Name (eCommerce)
Casein kinase I isoform delta
RefSeq ID
NM_001893
RefSeq Synonyms
NM_139062, NM_001893, BC015775, BC003558,
Research Areas
Breast Cancer,Cancer,Cell Cycle,Cytoskeleton,DNA Damage/Repair,EPO Signaling,FoxO Signaling,Golgi Apparatus,Hedgehog Signaling,Hippo Signaling,Immunology,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,p53 Signaling,Signal Transduction,VEGF Signaling,Wnt Signaling
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
CKI delta is a member of the casein kinase 1 (CK1) serine/threonine kinase family of proteins. In mammals, there are seven distinct genes that represent the CK1 family: alpha, beta, gamma-1, gamma-2, gamma-3, delta, and epsilon. CKI delta phosphorylates a number of proteins some of which include the circadian proteins period 1 and period 2. CKI delta is also involved in the Wnt signaling pathway.
UniGene ID
Hs.631725
UniProt ID (eCommerce)
P48730
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.