human CRYZ shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CRYZ.
shAAV-206081
AAV-h-CRYZ-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CRYZ (crystallin zeta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist.
Gene ID
1429
Gene Name (Vector)
crystallin zeta
Gene Symbol
CRYZ
HGNC ID
HGNC:2419
ORF Size (aa)
990
ORF Size (bp)
990 bp
RefSeq ID
NM_001889
RefSeq Synonyms
NM_001889, NM_001134759, NM_001130043, NM_001130042, BC070058, BC039578,
Species
human
UniGene ID
Hs.83114
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.