human CRYM shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CRYM.
shAAV-206080
AAV-h-CRYM-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CRYM (crystallin mu). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DFNA40; THBP
Description (Vector)
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.
Gene ID
1428
Gene Name (Vector)
crystallin mu
Gene Symbol
CRYM
HGNC ID
HGNC:2418
ORF Size (aa)
945
ORF Size (bp)
945 bp
RefSeq ID
NM_001888
RefSeq Synonyms
NM_001888, NM_001014444, BC018061,
Species
human
UniGene ID
Hs.924
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.