human CRTAC1 shRNA silencing AAV

Name
AAV-h-CRTAC1-shRNA

Cat No
shAAV-206035

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CRTAC1.

shAAV-206035

AAV-h-CRTAC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CRTAC1 (cartilage acidic protein 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ASPIC; ASPIC1; CEP-68

Description (Vector)

CRTAC1 encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.

Gene ID

55118

Gene Name (Vector)

cartilage acidic protein 1

Gene Symbol

CRTAC1

HGNC ID

HGNC:14882

ORF Size (aa)

1356

ORF Size (bp)

1356 bp

RefSeq ID

NM_018058

RefSeq Synonyms

NM_018058, NM_001206528, BC034245,

Species

human

UniGene ID

Hs.500736

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.