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human CRLF3 shRNA silencing AAV

Name 
AAV-h-CRLF3-shRNA
Cat No 
shAAV-206026
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CRLF3.

shAAV-206026
AAV-h-CRLF3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CRLF3 (cytokine receptor like factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CREME-9; CREME9; CRLM9; CYTOR4; FRWS; p48.2
Description (Vector)
CRLF3 encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. CRLF3 is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.
Gene ID
51379
Gene Name (Vector)
cytokine receptor like factor 3
Gene Symbol
CRLF3
HGNC ID
HGNC:17177
ORF Size (aa)
1329
ORF Size (bp)
1329 bp
RefSeq ID
NM_015986
RefSeq Synonyms
NM_015986, BC023567,
Species
human
UniGene ID
Hs.370168

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.