human CRHR1 shRNA silencing AAV

Name
AAV-h-CRHR1-shRNA

Cat No
shAAV-205997

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CRHR1.

shAAV-205997

AAV-h-CRHR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CRHR1 (corticotropin releasing hormone receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L

Description (Vector)

CRHR1 encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which represents a read-through transcript with the neighboring gene MGC57346.

Gene ID

1394

Gene Name (Vector)

corticotropin releasing hormone receptor 1

Gene Symbol

CRHR1

HGNC ID

HGNC:2357

ORF Size (aa)

1248

ORF Size (bp)

1248 bp

RefSeq ID

NM_004382

RefSeq Synonyms

NM_004382, NM_001303020, NM_001303018, NM_001145148, NM_001145147, NM_001145146, BC096836,

Species

human

UniGene ID

Hs.417628

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.