human CRHBP shRNA silencing AAV

Name 
AAV-h-CRHBP-shRNA
Cat No 
shAAV-205996
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CRHBP.

shAAV-205996
AAV-h-CRHBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CRHBP (corticotropin releasing hormone binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CRF-BP; CRFBP
Description (Vector)
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Gene ID
1393
Gene Name (Vector)
corticotropin releasing hormone binding protein
Gene Symbol
CRHBP
HGNC ID
HGNC:2356
ORF Size (aa)
969
ORF Size (bp)
969 bp
RefSeq ID
NM_001882
RefSeq Synonyms
NM_001882, BC018038,
Species
human
UniGene ID
Hs.115617

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.