human CRBN shRNA silencing AAV

Name
AAV-h-CRBN-shRNA

Cat No
shAAV-205967

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CRBN.

shAAV-205967

AAV-h-CRBN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CRBN (cereblon). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MRT2; MRT2A

Description (Vector)

CRBN encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

51185

Gene Name (Vector)

cereblon

Gene Symbol

CRBN

HGNC ID

HGNC:30185

ORF Size (aa)

1329

ORF Size (bp)

1329 bp

RefSeq ID

NM_016302

RefSeq Synonyms

NM_016302, NM_001173482, BC067811, BC017419,

Species

human

UniGene ID

Hs.18925

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.