human CPSF7 shRNA silencing AAV

Name 
AAV-h-CPSF7-shRNA
Cat No 
shAAV-205936
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CPSF7.

shAAV-205936
AAV-h-CPSF7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CPSF7 (cleavage and polyadenylation specific factor 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CFIm59; cleavage and polyadenylation specificity factor 59 kDa subunit; cleavage and polyadenylation specificity factor subunit 7; cleavage factor Im complex 59 kDa subunit; CPSF 59 kDa subunit; pre-mRNA cleavage factor I, 59 kDa subunit; pre-mRNA cleavage factor Im 59 kDa subunit
Description (eCommerce)
CPSF59 is the the 59 kDa subunit of the cleavage factor Im complex (CFIm). The CFIm is a heterodimer composed of a 25 kDa (CPSF5) subunit and either the 59 kDa (CPSF7) or 68 kDa (CPSF6) subunit and is essential to the first step of pre-mRNA 3’-end processing. CPSF59 bears an RNA-recognition motif (RRM).
Gene ID
79869
Gene Name (eCommerce)
cleavage and polyadenylation specific factor 7
Gene Name (Vector)
cleavage and polyadenylation specific factor 7
Gene Symbol
CPSF7
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1416
ORF Size (bp)
1416 bp
Protein Name (eCommerce)
Cleavage and polyadenylation specificity factor subunit 7
RefSeq ID
NM_024811
RefSeq Synonyms
NM_024811, NM_001142565, NM_001136040, BC018135,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Spliceosome
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
CPSF59 is the the 59 kDa subunit of the cleavage factor Im complex (CFIm). The CFIm is a heterodimer composed of a 25 kDa (CPSF5) subunit and either the 59 kDa (CPSF7) or 68 kDa (CPSF6) subunit and is essential to the first step of pre-mRNA 3’-end processing. CPSF59 bears an RNA-recognition motif (RRM).
UniGene ID
Hs.444552
UniProt ID (eCommerce)
Q8N684

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.