human CPOX shRNA silencing AAV

Name 
AAV-h-CPOX-shRNA
Cat No 
shAAV-205919
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CPOX.

shAAV-205919
AAV-h-CPOX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CPOX (coproporphyrinogen oxidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CPO; CPX; HCP
Description (Vector)
CPOX is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
Gene ID
1371
Gene Name (Vector)
coproporphyrinogen oxidase
Gene Symbol
CPOX
HGNC ID
HGNC:2321
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
RefSeq ID
NM_000097
RefSeq Synonyms
NM_000097, BC023554, BC023551, BC017210,
Species
human
UniGene ID
Hs.476982

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.