human CPNE3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CPNE3.
shAAV-205905
AAV-h-CPNE3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CPNE3 (copine 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
copine III; copine-3; CPN3; PRO1071
Description (eCommerce)
CPNE3 encodes the calcium-dependent phospholipid-binding protein, Copine-3. Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. The A domain-like sequence in the carboxy-terminus mediates interactions between integrins and extracellular ligands [taken from NCBI Entrez Gene (Gene ID: 8895)].
Description (Vector)
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a protein which contains two type II C2 domains in the amino-terminus and an A domain-like sequence in the carboxy-terminus. The A domain mediates interactions between integrins and extracellular ligands.
Gene ID
8895
Gene Name (eCommerce)
copine 3
Gene Name (Vector)
copine 3
Gene Symbol
CPNE3
HGNC ID
HGNC:2316
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1614
ORF Size (bp)
1614 bp
Protein Name (eCommerce)
Copine-3
RefSeq ID
NM_003909
RefSeq Synonyms
NM_003909, BC066597, BC036242, BC015734,
Research Areas
Cell Biology,Metabolism/Metabolic Process,Translational Control,Transport
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
CPNE3 encodes the calcium-dependent phospholipid-binding protein, Copine-3. Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. The A domain-like sequence in the carboxy-terminus mediates interactions between integrins and extracellular ligands [taken from NCBI Entrez Gene (Gene ID: 8895)].
UniGene ID
Hs.191219
UniProt ID (eCommerce)
O75131
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.