human CPEB1 shRNA silencing AAV

Name
AAV-h-CPEB1-shRNA

Cat No
shAAV-205883

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CPEB1.

shAAV-205883

AAV-h-CPEB1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CPEB1 (cytoplasmic polyadenylation element binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CPE-BP1; CPEB; CPEB-1; h-CPEB; hCPEB-1

Description (Vector)

CPEB1 encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

64506

Gene Name (Vector)

cytoplasmic polyadenylation element binding protein 1

Gene Symbol

CPEB1

HGNC ID

HGNC:21744

ORF Size (aa)

1686

ORF Size (bp)

1686 bp

RefSeq ID

NM_030594

RefSeq Synonyms

NM_030594, NM_001288820, NM_001288819, NM_001079535, NM_001079534, NM_001079533, BC050629, BC035348,

Species

human

UniGene ID

Hs.547988

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.