human CP110 shRNA silencing AAV

Name
AAV-h-CP110-shRNA

Cat No
shAAV-205867

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CCP110.

shAAV-205867

AAV-h-CP110-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CCP110 (centriolar coiled-coil protein 110). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

centriolar coiled-coil protein 110kDa; centriolar coiled-coil protein of 110 kDa; centrosomal protein CP110; centrosomal protein of 110 kDa; Cep110; CP110

Description (eCommerce)

CP110 is a protein required for centrosome duplication and for correct spindle formation. CP110 is a substrate of CDKs and is a cell cycle regulated protein ubiquitinated by SCF.

Gene ID

9738

Gene Name (eCommerce)

centriolar coiled-coil protein 110

Gene Name (Vector)

centriolar coiled-coil protein 110

Gene Symbol

CCP110

HGNC ID

HGNC:24342

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2976

ORF Size (bp)

2976 bp

Protein Name (eCommerce)

Centriolar coiled-coil protein of 110 kDa

RefSeq ID

NM_014711

RefSeq Synonyms

NM_014711, NM_001323577, NM_001323576, NM_001323572, NM_001323571, NM_001323570, NM_001323569, NM_001199022, BC036654,

Research Areas

Cell Cycle,Cell Division,Cytoskeleton,Replication,Transport

Research Areas (Faceted)

cell_biology,cell_cycle,genetics

Species

human

Target Sentence

CP110 is a protein required for centrosome duplication and for correct spindle formation. CP110 is a substrate of CDKs and is a cell cycle regulated protein ubiquitinated by SCF.

UniGene ID

Hs.279912

UniProt ID (eCommerce)

O43303

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.