human COL4A5 shRNA silencing AAV

Name 
AAV-h-COL4A5-shRNA
Cat No 
shAAV-205708
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human COL4A5.

shAAV-205708
AAV-h-COL4A5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human COL4A5 (collagen type IV alpha 5 chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASLN; ATS; CA54
Description (Vector)
COL4A5 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.
Gene ID
1287
Gene Name (Vector)
collagen type IV alpha 5 chain
Gene Symbol
COL4A5
HGNC ID
HGNC:2207
ORF Size (aa)
5076
ORF Size (bp)
5076 bp
RefSeq ID
NM_000495
RefSeq Synonyms
NM_033380, NM_000495, BC151846,
Species
human
UniGene ID
Hs.369089

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.