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human COG3 shRNA silencing AAV

Name 
AAV-h-COG3-shRNA
Cat No 
shAAV-205668
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human COG3.

shAAV-205668
AAV-h-COG3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human COG3 (component of oligomeric golgi complex 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COG complex subunit 3; Component of oligomeric Golgi complex 3; conserved oligomeric Golgi complex subunit 3; p94; SEC34; tethering factor SEC34; vesicle-docking protein SEC34 homolog
Description (eCommerce)
Conserved oligomeric Golgi complex subunit 3 (COG3) is a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. CO3G is involved in ER-Golgi transport [taken from NCBI Entrez Gene (Gene ID: 83548)].
Description (Vector)
COG3 encodes a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. The protein encoded by this gene is involved in ER-Golgi transport.
Gene ID
83548
Gene Name (eCommerce)
component of oligomeric golgi complex 3
Gene Name (Vector)
component of oligomeric golgi complex 3
Gene Symbol
COG3
HGNC ID
HGNC:18619
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
Protein Name (eCommerce)
Conserved oligomeric Golgi complex subunit 3
RefSeq ID
NM_031431
RefSeq Synonyms
NM_031431, BC038953,
Research Areas
Golgi Apparatus,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Conserved oligomeric Golgi complex subunit 3 (COG3) is a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. CO3G is involved in ER-Golgi transport [taken from NCBI Entrez Gene (Gene ID: 83548)].
UniGene ID
Hs.507948
UniProt ID (eCommerce)
Q96JB2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.