human COG1 shRNA silencing AAV

Name
AAV-h-COG1-shRNA

Cat No
shAAV-205664

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human COG1.

shAAV-205664

AAV-h-COG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human COG1 (component of oligomeric golgi complex 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CDG2G; LDLB

Description (Vector)

COG1 is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.

Gene ID

9382

Gene Name (Vector)

component of oligomeric golgi complex 1

Gene Symbol

COG1

HGNC ID

HGNC:6545

ORF Size (aa)

2943

ORF Size (bp)

2943 bp

RefSeq ID

NM_018714

RefSeq Synonyms

NM_018714, BC047465, BC021985,

Species

human

UniGene ID

Hs.283109

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.