human CNOT7 shRNA silencing AAV

Name 
AAV-h-CNOT7-shRNA
Cat No 
shAAV-205614
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CNOT7.

shAAV-205614
AAV-h-CNOT7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CNOT7 (CCR4-NOT transcription complex subunit 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAF-1; CAF1; Caf1a; hCAF-1
Description (Vector)
CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Gene ID
29883
Gene Name (Vector)
CCR4-NOT transcription complex subunit 7
Gene Symbol
CNOT7
HGNC ID
HGNC:14101
ORF Size (aa)
741
ORF Size (bp)
741 bp
RefSeq ID
NM_013354
RefSeq Synonyms
NM_054026, NM_013354, NM_001322100, NM_001322099, NM_001322098, NM_001322097, NM_001322096, NM_001322095, NM_001322094, NM_001322093, NM_001322092, NM_001322091, NM_001322090, NM_001322089, NM_001322088, NM_001322087, BC070187, BC060852, BC007315,
Species
human
UniGene ID
Hs.598387

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.