human CNO shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BLOC1S4.
shAAV-205602
AAV-h-CNO-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BLOC1S4 (biogenesis of lysosomal organelles complex 1 subunit 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BCAS4L; BLOS4; CNO
Description (Vector)
This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and is a model for Hermansky-Pudlak syndrome. The encoded protein may play a role in intracellular vesicular trafficking.
Gene ID
55330
Gene Name (Vector)
biogenesis of lysosomal organelles complex 1 subunit 4
Gene Symbol
BLOC1S4
HGNC ID
HGNC:24206
ORF Size (aa)
654
RefSeq ID
NM_018366
RefSeq Synonyms
NM_018366, BC067815,
Species
human
UniGene ID
Hs.7570
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.