human CLRN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CLRN1.
shAAV-205506
AAV-h-CLRN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CLRN1 (clarin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RP61; USH3; USH3A
Description (Vector)
CLRN1 encodes a protein that contains a cytosolic N-terminus, multiple helical transmembrane domains, and an endoplasmic reticulum membrane retention signal, TKGH, in the C-terminus. The encoded protein may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIIa. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
7401
Gene Name (Vector)
clarin 1
Gene Symbol
CLRN1
HGNC ID
HGNC:12605
ORF Size (aa)
699
ORF Size (bp)
699 bp
RefSeq ID
NM_052995
RefSeq Synonyms
NM_174878, NM_052995, NM_001256819, NM_001195794, BC074971, BC074970,
Species
human
UniGene ID
Hs.380222
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.