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human CLPTM1L shRNA silencing AAV

Name 
AAV-h-CLPTM1L-shRNA
Cat No 
shAAV-205503
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CLPTM1L.

shAAV-205503
AAV-h-CLPTM1L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLPTM1L (CLPTM1 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cisplatin resistance related protein CRR9p; cisplatin resistance-related protein 9; cleft lip and palate transmembrane protein 1-like protein; CLPTM1-like protein; CRR9; CRR9p
Description (eCommerce)
CLPTM1L is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in its coding sequence have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015] [taken from NCBI Entrez Gene (Gene ID: 81037)].
Gene ID
81037
Gene Name (eCommerce)
CLPTM1 like
Gene Name (Vector)
CLPTM1 like
Gene Symbol
CLPTM1L
HGNC ID
HGNC:24308
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1617
ORF Size (bp)
1617 bp
Protein Name (eCommerce)
Cleft lip and palate transmembrane protein 1-like protein
RefSeq ID
NM_030782
RefSeq Synonyms
NM_030782, BC025305,
Research Areas
Apoptosis
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
CLPTM1L is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in its coding sequence have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015] [taken from NCBI Entrez Gene (Gene ID: 81037)].
UniGene ID
Hs.444673
UniProt ID (eCommerce)
Q96KA5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.