human CLN3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CLN3.
shAAV-205480
AAV-h-CLN3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CLN3 (CLN3, battenin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BTN1; BTS; JNCL
Description (Vector)
CLN3 encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.
Gene ID
1201
Gene Name (Vector)
CLN3, battenin
Gene Symbol
CLN3
HGNC ID
HGNC:2074
ORF Size (aa)
1083
ORF Size (bp)
1083 bp
RefSeq ID
NM_000086
RefSeq Synonyms
NM_001286110, NM_001286109, NM_001286105, NM_001286104, NM_001042432, NM_000086, BC111068, BC004433, BC002394,
Species
human
UniGene ID
Hs.628393
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.