human CLIC3 shRNA silencing AAV

Name
AAV-h-CLIC3-shRNA

Cat No
shAAV-205453

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CLIC3.

shAAV-205453

AAV-h-CLIC3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLIC3 (chloride intracellular channel 3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.

Gene ID

9022

Gene Name (Vector)

chloride intracellular channel 3

Gene Symbol

CLIC3

HGNC ID

HGNC:2064

ORF Size (aa)

711

ORF Size (bp)

711 bp

RefSeq ID

NM_004669

RefSeq Synonyms

NM_004669, BC007012,

Species

human

UniGene ID

Hs.64746

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.