human ETFB shRNA silencing AAV

Name
AAV-h-ETFB-shRNA

Cat No
shAAV-205395

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ETFB.

shAAV-205395

AAV-h-ETFB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ETFB (electron transfer flavoprotein beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

80

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

beta-ETF; electron transfer flavoprotein beta subunit; electron transfer flavoprotein subunit beta; electron transfer flavoprotein, beta polypeptide; electron-transferring-flavoprotein, beta polypeptide; FP585; MADD

Description (eCommerce)

ETFB is the electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase [taken from NCBI Entrez Gene (Gene ID: 2109)].

Description (Vector)

ETFB encodes electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. The gene deficiencies have been implicated in type II glutaricaciduria. Alternatively spliced transcript variants have been found for this gene.

Gene ID

2109

Gene Name (eCommerce)

electron transfer flavoprotein subunit beta

Gene Name (Vector)

electron transfer flavoprotein beta subunit

Gene Symbol

ETFB

HGNC ID

HGNC:3482

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

768

ORF Size (bp)

768 bp

Protein Name (eCommerce)

Electron transfer flavoprotein subunit beta

RefSeq ID

NM_001985

RefSeq Synonyms

NM_001985, NM_001014763, BC093963, BC093961,

Research Areas

Metabolism/Metabolic Process,Mitochondrion

Research Areas (Faceted)

cell_biology,metabolism

Species

human

Target Sentence

ETFB is the electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase [taken from NCBI Entrez Gene (Gene ID: 2109)].

UniGene ID

Hs.348531

UniProt ID (eCommerce)

P38117

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.