human CLCN5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CLCN5.
shAAV-205354
AAV-h-CLCN5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CLCN5 (chloride voltage-gated channel 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ClC-5; CLC5; CLCK2; DENTS; hCIC-K2; NPHL1; NPHL2; XLRH; XRN
Description (Vector)
CLCN5 encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.)
Gene ID
1184
Gene Name (Vector)
chloride voltage-gated channel 5
Gene Symbol
CLCN5
HGNC ID
HGNC:2023
ORF Size (aa)
2241
ORF Size (bp)
2241 bp
RefSeq ID
NM_000084
RefSeq Synonyms
NM_001282163, NM_001272102, NM_001127899, NM_001127898, NM_000084, BC130431, BC130429,
Species
human
UniGene ID
Hs.166486
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.