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human CITED2 shRNA silencing AAV

Name 
AAV-h-CITED2-shRNA
Cat No 
shAAV-205300
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CITED2.

shAAV-205300
AAV-h-CITED2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASD8; MRG-1; MRG1; P35SRJ; VSD2
Description (Vector)
CITED2 inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
10370
Gene Name (Vector)
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
Gene Symbol
CITED2
HGNC ID
HGNC:1987
ORF Size (aa)
813
ORF Size (bp)
813 bp
RefSeq ID
NM_006079
RefSeq Synonyms
NM_006079, NM_001168389, NM_001168388, BC004377,
Species
human
UniGene ID
Hs.82071

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.