human CISD1 shRNA silencing AAV

Name
AAV-h-CISD1-shRNA

Cat No
shAAV-205290

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CISD1.

shAAV-205290

AAV-h-CISD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CISD1 (CDGSH iron sulfur domain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C10orf70; MDS029; mitoNEET; ZCD1

Description (Vector)

CISD1 encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active (2Fe-2S) cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2.

Gene ID

55847

Gene Name (Vector)

CDGSH iron sulfur domain 1

Gene Symbol

CISD1

HGNC ID

HGNC:30880

ORF Size (aa)

327

RefSeq ID

NM_018464

RefSeq Synonyms

NM_018464, BC059168, BC008474, BC007043, BC005962,

Species

human

UniGene ID

Hs.370102

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.