human CIC shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CIC.
shAAV-205279
AAV-h-CIC-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CIC (capicua transcriptional repressor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MRD45; protein capicua homolog
Description (eCommerce)
CIC/Capicua is the ortholog of the drosophila capicua which is a transcriptional repressor involved in epidermal growth factor receptor (EGFR) signaling, developmental patterning, and cell fate. In humans, CIC/Capicua may be involved in granule cell lineage and medulloblastoma tumorigenesis.
Gene ID
23152
Gene Name (eCommerce)
capicua transcriptional repressor
Gene Name (Vector)
capicua transcriptional repressor
Gene Symbol
CIC
HGNC ID
HGNC:14214
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4824
ORF Size (bp)
4824 bp
Protein Name (eCommerce)
Protein capicua homolog
RefSeq ID
NM_015125
RefSeq Synonyms
NM_015125, NM_001304815, BC140443,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
CIC/Capicua is the ortholog of the drosophila capicua which is a transcriptional repressor involved in epidermal growth factor receptor (EGFR) signaling, developmental patterning, and cell fate. In humans, CIC/Capicua may be involved in granule cell lineage and medulloblastoma tumorigenesis.
UniGene ID
Hs.388236
UniProt ID (eCommerce)
Q96RK0
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.