human CIAPIN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CIAPIN1.
shAAV-205266
AAV-h-CIAPIN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CIAPIN1 (cytokine induced apoptosis inhibitor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Anamorsin; CIAE2; Cytokine-induced apoptosis inhibitor 1; DRE2; fe-S cluster assembly protein DRE2 homolog; predicted protein of HQ0915; PRO0915
Description (eCommerce)
CIAPIN1 (cytokine-induced apoptosis inhibitor 1) is also known as Anamorsin. CIAPIN1 may be required for the maturation of extramitochondrial Fe/S proteins. CIAPIN1 has anti-apoptotic effects in the cell, and is involved in negative control of cell death upon cytokine withdrawal. CIAPIN1 also promotes development of hematopoietic cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q6FI81].
Description (Vector)
CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 (PubMed 14970183)).(supplied by OMIM, Mar 2008)
Gene ID
57019
Gene Name (eCommerce)
cytokine induced apoptosis inhibitor 1
Gene Name (Vector)
cytokine induced apoptosis inhibitor 1
Gene Symbol
CIAPIN1
HGNC ID
HGNC:28050
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
939
ORF Size (bp)
939 bp
Protein Name (eCommerce)
Anamorsin
RefSeq ID
NM_020313
RefSeq Synonyms
NM_020313, NM_001308358, NM_001308347, BC071740, BC067303, BC024196, BC002568,
Research Areas
Apoptosis,Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
CIAPIN1 (cytokine-induced apoptosis inhibitor 1) is also known as Anamorsin. CIAPIN1 may be required for the maturation of extramitochondrial Fe/S proteins. CIAPIN1 has anti-apoptotic effects in the cell, and is involved in negative control of cell death upon cytokine withdrawal. CIAPIN1 also promotes development of hematopoietic cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q6FI81].
UniGene ID
Hs.4900
UniProt ID (eCommerce)
Q6FI81
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.