human CHST11 shRNA silencing AAV

Name
AAV-h-CHST11-shRNA

Cat No
shAAV-205237

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CHST11.

shAAV-205237

AAV-h-CHST11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CHST11 (carbohydrate sulfotransferase 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C4ST; C4ST-1; C4ST1; HSA269537

Description (Vector)

CHST11 belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

50515

Gene Name (Vector)

carbohydrate sulfotransferase 11

Gene Symbol

CHST11

HGNC ID

HGNC:17422

ORF Size (aa)

1059

ORF Size (bp)

1059 bp

RefSeq ID

NM_018413

RefSeq Synonyms

NM_018413, NM_001173982, BC013315,

Species

human

UniGene ID

Hs.17569

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.