human CHRM4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CHRM4.
shAAV-205202
AAV-h-CHRM4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CHRM4 (cholinergic receptor muscarinic 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HM4; M4R
Description (Vector)
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition.
Gene ID
1132
Gene Name (Vector)
cholinergic receptor muscarinic 4
Gene Symbol
CHRM4
HGNC ID
HGNC:1953
ORF Size (aa)
1440
ORF Size (bp)
1440 bp
RefSeq ID
NM_000741
RefSeq Synonyms
NM_000741, BC137535,
Species
human
UniGene ID
Hs.248100
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.